Former European Council president Donald Tusk says Brussels feels “empathy” towards an independent Scotland joining the European Union.
Nicola Sturgeon has said an independent Scotland would seek full EU membership.
When asked if this would be looked upon favourably, Mr Tusk said, “emotionally I have no doubt that everyone will be enthusiastic”.
It came as other European leaders expressed sadness at the UK leaving the EU.
French President Emmanuel Macron said he was “deeply sad” while the EU’s Guy Verhofstadt pledged to try and “ensure the EU is a project you’ll want to be a part of again”.
But Mr Tusk warned that any future entry bid on the part of an independent Scotland would not be automatically accepted.
Mr Tusk’s comments come after his predecessor, Herman Van Rompuy, last year said he believes Brexit has changed EU attitudes to Scottish independence.
The UK government does not support Scottish government calls for another independence referendum or rejoining the EU in any form.
Britain officially left the European Union on Friday at 23:00 GMT after 47 years of membership, and more than three years after it voted to do so in a referendum.
Scotland voted in favour of the UK staying in the EU by 62% to 38% in 2016.
Mr Tusk, who served as European Council president for five years until November last year, was speaking in a BBC interview to be aired on The Andrew Marr Show.
When asked about the prospect of an independent Scotland joining the EU, the Polish politician said “I want to stop myself from saying something too blunt”.
He said that he feels “very Scottish, especially after Brexit”.
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However he added he had to “respect the internal debate in the United Kingdom” and it was not his role to intervene.
But when pressed on the level of support in the EU towards an independent Scotland joining the union, he said: “Emotionally I have no doubt that everyone will be enthusiastic here in Brussels, and more generally in Europe.
“If you ask me about our emotions, you will witness I think always empathy.”
Mr Tusk also said “formalities” and treaty agreements would still need to be adhered to.