June 16, 2021

Coronavirus: Scientists race to develop a vaccine

A deadly new virus. Thousands of people infected. No cure. No vaccine.

We’ve been here many times before.

In the past five years alone, the world has faced outbreaks of Ebola, Zika, another coronavirus called Mers (Middle East Respiratory Syndrome), and now the virus simply known as “2019-nCoV”.

It’s already infected thousands of people and killed more than 100.

But unlike in many previous outbreaks, where vaccines to protect people have taken years to develop, research for a vaccine to help stem this outbreak got under way within hours of the virus being identified.

Chinese officials released its genetic code very quickly. That information helps scientists determine where the virus probably came from, how it might mutate as the outbreak develops, and how to protect people against it.

With technological advances and greater commitment from governments around the world to fund research on emerging diseases, research facilities were able to spring into action fast.

Unprecedented speed
At Inovio’s lab in San Diego, scientists are using a relatively new type of DNA technology to develop a potential vaccine. “INO-4800 ” – as it’s currently called – with plans for it to enter human trials by the early summer.

Kate Broderick, senior vice-president of research and development at Inovio, said: “Once China had provided the DNA sequence of this virus, we were able to put it through our lab’s computer technology and design a vaccine within three hours.

“Our DNA medicine vaccines are novel in that they use DNA sequences from the virus to target specific parts of the pathogen which we believe the body will mount the strongest response to.

“We then use the patient’s own cells to become a factory for the vaccine, strengthening the body’s own natural response mechanisms.”

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